CTPS2 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP13030b
Catalog Number: AC-AP13030b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32822
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB32822
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
Other Names:
CTP synthase 2, CTP synthetase 2, UTP--ammonia ligase 2, CTPS2
Target/Specificity:
This CTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 450-479 amino acids from the C-terminal region of human CTPS2.
Antigen Region:
450-479
Antigen Type: Synthetic Peptide
Gene Name: CTPS2
Gene ID: 56474
Primary Accession: Q9NRF8
NCBI Accession: NP_001137474.1;NP_062831.3;NP_787055.1
Other Accession: Q1RMS2; NP_787055.1; NP_062831.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
Other Names:
CTP synthase 2, CTP synthetase 2, UTP--ammonia ligase 2, CTPS2
Target/Specificity:
This CTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 450-479 amino acids from the C-terminal region of human CTPS2.
Antigen Region:
450-479
Antigen Type: Synthetic Peptide
Gene Name: CTPS2
Gene ID: 56474
Primary Accession: Q9NRF8
NCBI Accession: NP_001137474.1;NP_062831.3;NP_787055.1
Other Accession: Q1RMS2; NP_787055.1; NP_062831.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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