CTRP5 polyclonal, anti-human

Quantity: 100 µl

Description:
CTRP5 (C1qTNF-related protein 5; C1QTNF5) belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase (AMPK) in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD).

Synonyms:
Complement C1q Tumor Necrosis Factor-related Protein 5, C1QTNF5

Isotype: Guinea pig Polyclonal

Immunogen:
Recombinant human CTRP5.

Form: Purified, in 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.

Specificity:
Recognizes a N-terminal region of CTRP5 full-length protein. Detects bands of ~15kDa and ~26kDa by Western blot. This antibody is CTRP5-specific.

Reactivity: human

Applications: ELISA, Immunoprecipitation, Western Blot

Working DIlution: Optimal conditions must be determined individually for each application.

Storage: 2-8C immediate use, or -20C (aliquoted)