CTSE Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP6568c
Background:
CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen.
Other Names:
Cathepsin E, Cathepsin E form I, Cathepsin E form II, CTSE
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6568c was selected from the Center region of human CTSE. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CTSE
Gene ID: 1510
Primary Accession: P14091
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen.
Other Names:
Cathepsin E, Cathepsin E form I, Cathepsin E form II, CTSE
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP6568c was selected from the Center region of human CTSE. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CTSE
Gene ID: 1510
Primary Accession: P14091
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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