CTSE polyclonal (Center), anti-human, mouse, rat
€0.00
In stock
SKU
AC-AP6568c
Catalog Number: AC-AP6568c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19246
Applications: WB, FC, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19246
Applications: WB, FC, IHC-P
Datasheet
Request Information
Background:
CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen.
Other Names:
Cathepsin E, Cathepsin E form I, Cathepsin E form II, CTSE
Target/Specificity:
This CTSE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-187 amino acids from the Central region of human CTSE.
Antigen Region:
157-187
Antigen Type: Synthetic Peptide
Gene Name: CTSE
Gene ID: 1510
Primary Accession: P14091
NCBI Accession: NP_001901.1;NP_683865.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen.
Other Names:
Cathepsin E, Cathepsin E form I, Cathepsin E form II, CTSE
Target/Specificity:
This CTSE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-187 amino acids from the Central region of human CTSE.
Antigen Region:
157-187
Antigen Type: Synthetic Peptide
Gene Name: CTSE
Gene ID: 1510
Primary Accession: P14091
NCBI Accession: NP_001901.1;NP_683865.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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