CTSK antibody (clone 2F1), anti-human
€435.00
In stock
SKU
AC-AT1681a
Catalog Number: AC-AT1681a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
Request Information AC-AT1681a">Request Information
Background:
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Other Names:
Cathepsin K, Cathepsin O, Cathepsin O2, Cathepsin X, CTSK, CTSO, CTSO2
Antigen Type:
Recombinant Protein
Gene Name: CTSK
Gene ID: 1513
NCBI Accession: NP_000387.1
Primary Accession: P43235
Other Accession: BC016058
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Other Names:
Cathepsin K, Cathepsin O, Cathepsin O2, Cathepsin X, CTSK, CTSO, CTSO2
Antigen Type:
Recombinant Protein
Gene Name: CTSK
Gene ID: 1513
NCBI Accession: NP_000387.1
Primary Accession: P43235
Other Accession: BC016058
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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