CTSK Polyclonal Antibody

Background:
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

Research Area: Cancer, Cell Biology, Cardiovascular, Neuroscience, Signal Transduction

Synonyms:
CTSK, CTS02, CTSO, CTSO1, CTSO2, PKND, PYCD

Immunogen: Recombinant fusion protein of human CTSK (NP_000387.1).

Swissprot: P43235
Gene ID: 1513

Calculated MW: 36 kDa
Observed MW: 41 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.