CTSK polyclonal (Center R222), anti-human, mouse
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In stock
SKU
AC-AP7381c
Catalog Number: AC-AP7381c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19254
Applications: IHC-P, FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19254
Applications: IHC-P, FC, WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Other Names:
Cathepsin K, Cathepsin O, Cathepsin O2, Cathepsin X, CTSK, CTSO, CTSO2
Target/Specificity:
This CTSK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-237 amino acids from the Central region of human CTSK.
Antigen Region:
207-237
Antigen Type: Synthetic Peptide
Gene Name: CTSK
Gene ID: 1513
Primary Accession: P43235
NCBI Accession: NP_000387.1
Other Accession: P43236; Q9GLE3; P61276; Q5E968
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Other Names:
Cathepsin K, Cathepsin O, Cathepsin O2, Cathepsin X, CTSK, CTSO, CTSO2
Target/Specificity:
This CTSK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-237 amino acids from the Central region of human CTSK.
Antigen Region:
207-237
Antigen Type: Synthetic Peptide
Gene Name: CTSK
Gene ID: 1513
Primary Accession: P43235
NCBI Accession: NP_000387.1
Other Accession: P43236; Q9GLE3; P61276; Q5E968
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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