CUGBP1 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP14036a
Background:
Members of the CELF/BRUNOL protein family contain twoN-terminal RNA recognition motif (RRM) domains, one C-terminal RRMdomain, and a divergent segment of 160-230 aa between the secondand third RRM domains. Members of this protein family regulatepre-mRNA alternative splicing and may also be involved in mRNAediting, and translation. This gene may play a role in myotonicdystrophy type 1 (DM1) via interactions with the dystrophiamyotonica-protein kinase (DMPK) gene. Alternative splicing resultsin multiple transcript variants encoding different isoforms.
Other Names:
CUGBP Elav-like family member 1, CELF-1, 50 kDa nuclear polyadenylated RNA-binding protein, Bruno-like protein 2, CUG triplet repeat RNA-binding protein 1, CUG-BP1, CUG-BP- and ETR-3-like factor 1, Deadenylation factor CUG-BP, Embryo deadenylation element-binding protein homolog, EDEN-BP homolog, RNA-binding protein BRUNOL-2, CELF1, BRUNOL2, CUGBP, CUGBP1, NAB50
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14036a was selected from the N-term region of CUGBP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CELF1
Gene ID: 10658
Primary Accession: Q92879
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Members of the CELF/BRUNOL protein family contain twoN-terminal RNA recognition motif (RRM) domains, one C-terminal RRMdomain, and a divergent segment of 160-230 aa between the secondand third RRM domains. Members of this protein family regulatepre-mRNA alternative splicing and may also be involved in mRNAediting, and translation. This gene may play a role in myotonicdystrophy type 1 (DM1) via interactions with the dystrophiamyotonica-protein kinase (DMPK) gene. Alternative splicing resultsin multiple transcript variants encoding different isoforms.
Other Names:
CUGBP Elav-like family member 1, CELF-1, 50 kDa nuclear polyadenylated RNA-binding protein, Bruno-like protein 2, CUG triplet repeat RNA-binding protein 1, CUG-BP1, CUG-BP- and ETR-3-like factor 1, Deadenylation factor CUG-BP, Embryo deadenylation element-binding protein homolog, EDEN-BP homolog, RNA-binding protein BRUNOL-2, CELF1, BRUNOL2, CUGBP, CUGBP1, NAB50
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14036a was selected from the N-term region of CUGBP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CELF1
Gene ID: 10658
Primary Accession: Q92879
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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