CUL3 Polyclonal Antibody

Background:
This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research Area: Cancer, Cell Biology

Synonyms:
CUL 3, Cul-3, cul3, CUL3, Cullin-3, Cullin3, KIAA0617, PHA2E

Immunogen: Recombinant protein of human CUL3

Swissprot: Q13618
Gene Accession: BC039598

Calculated MW: 89 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-8556/sc-5322/sc-11385