CUL3 Polyclonal Antibody

Background:
This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Research Area: Cancer, Cell Biology

Synonyms:
CUL-3, PHA2E, CUL3, Cullin 3, cullin-3

Immunogen: Recombinant fusion protein of human CUL3 (NP_003581.1).

Swissprot: Q13618
Gene ID: 8452

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.