CUL4B polyclonal, anti-human, mouse, rat

Background:
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: CUL-4B, MRXHF2, MRXS15, MRXSC, SFM2

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human CUL4B

Gene Symbol: CUL4B

Gene ID: 8450

Swiss prot: Q13620

Calculated MW: 104kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.