CUL4B Polyclonal Antibody

Background:
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cell biology

Synonyms:
CUL 4B, CUL-4B, CUL4B, CUL4B, Cullin-4B, DKFZp686F1470, KIAA0695, MRXHF2, MRXSC, SFM2

Immunogen: Synthetic peptide of human CUL4B

Swissprot: Q13620
Gene Accession: NP_003579

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.9 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-8557/sc-5323/sc-10782