CUL4B Polyclonal Antibody

Background:
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cell biology

Synonyms:
CUL4B, CUL-4B, MRXHF2, MRXS15, MRXSC, SFM2, cullin-4B

Immunogen: Recombinant fusion protein of human CUL4B (NP_003579.3).

Swissprot: Q13620
Gene ID: 8450

Calculated MW: 84 kDa/102 kDa/103 kDa
Observed MW: 105 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.