CUL7 polyclonal, anti-human, rat

Background:
The protein encoded by this gene is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene. CUL-7 is highly expressed in fetal kidney and adult skeletal muscle in addition to abundant expression in fetal brain, and adult pancreas, kidney, placenta and heart. It is also detected in trophoblasts, lymphoblasts, osteoblasts, chondrocytes and skin fibroblasts.

Synonyms: 3M1, KIAA0076, dJ20C7.5

Cellular Location: cytoplasm

Immunogen:
Recombinant protein of human CUL7

Gene Symbol: CUL7

Gene ID: 9820

Swiss prot: Q14999

Calculated MW: 191kDa

Recommended dilution:
WB 1:200-1000, IHC 1:25-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.