Cullin 1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Cullin 1, also known as CUL1, is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination. This is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Human cullin 1, but not the other closely related cullins 2, 3, 4A, and 5, selectively interacts with human SKP1.

Description:
Rabbit IgG polyclonal antibody for Cullin-1 (CUL1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
CUL 1 antibody, CUL-1 antibody, CUL1 antibody, CUL1_HUMAN antibody, Cullin-1 antibody, Cullin1 antibody, MGC149834 antibody, MGC149835 antibody.

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Cullin 1 recombinant protein (Position: E457-D770). Human Cullin 1 shares 100% amino acid (aa) sequence identity with mouse Cullin 1.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.