CX3CL1 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60619
Background:
Chemokines are members of a superfamily of inducible, secreted, proinflammatory cytokines. Members of the chemokine family exhibit 20-50% homology in their predicted amino acid sequences and are divided into four subfamilies. In the subfamily designated C-C or β, the first two cysteines are adjacent. In the C-X-C or a subfamily, the first two of four cysteine residues are separated by a single amino acid. C subfamily members, also designated γ chemokines, lack the first and third cysteine residues of the conserved motif. Chemokines in these three subfamilies are small, secreted proteins with molecular weights ranging from 7-15 kDa. Fractalkine, also designated neurotactin, is the first characterized member of a fourth chemokine subfamily. Fractalkine contains a novel C-X3-C motif in which the first two cysteines are separated by three amino acid residues. Fractalkine mRNA has been detected in brain and heart and is upregulated in microglia and endothelial cells by inflammatory signals. The protein can exist both as a membranebound form and as a chemotactic soluble form.
Alternative Name:
Fractalkine, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1, ed into the following chain:Processed fractalkine, CX3CL1, FKN, NTT, SCYD1
Application Dilution: WB: 1:500~1:1000
Specificity: CX3CL1 polyclonal antibody detects endogenous levels of CX3CL1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CX3CL1
MW: ~ 42 kDa
Swis Prot.: P78423
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Chemokines are members of a superfamily of inducible, secreted, proinflammatory cytokines. Members of the chemokine family exhibit 20-50% homology in their predicted amino acid sequences and are divided into four subfamilies. In the subfamily designated C-C or β, the first two cysteines are adjacent. In the C-X-C or a subfamily, the first two of four cysteine residues are separated by a single amino acid. C subfamily members, also designated γ chemokines, lack the first and third cysteine residues of the conserved motif. Chemokines in these three subfamilies are small, secreted proteins with molecular weights ranging from 7-15 kDa. Fractalkine, also designated neurotactin, is the first characterized member of a fourth chemokine subfamily. Fractalkine contains a novel C-X3-C motif in which the first two cysteines are separated by three amino acid residues. Fractalkine mRNA has been detected in brain and heart and is upregulated in microglia and endothelial cells by inflammatory signals. The protein can exist both as a membranebound form and as a chemotactic soluble form.
Alternative Name:
Fractalkine, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1, ed into the following chain:Processed fractalkine, CX3CL1, FKN, NTT, SCYD1
Application Dilution: WB: 1:500~1:1000
Specificity: CX3CL1 polyclonal antibody detects endogenous levels of CX3CL1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human CX3CL1
MW: ~ 42 kDa
Swis Prot.: P78423
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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