CXCL1 Polyclonal Antibody

Background:
CXCL1 (C-X-C Motif Chemokine Ligand 1) is a Protein Coding gene. Diseases associated with CXCL1 include Melanoma and Bacterial Meningitis. Among its related pathways are Peptide ligand-binding receptors and Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions. GO annotations related to this gene include receptor binding and chemokine activity. An important paralog of this gene is CXCL2.This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.

Research Area: Cancer, Immunology

Synonyms:
C-X-C motif chemokine 1, Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), chemokine (C-X-C motif) ligand 1, CINC-1, CXCL1, Cytokine-induced neutrophil chemoattractant 1, Fibroblast secretory protein, Fsp, Gro 1, Gro A, Gro, GRO protein, alpha, GRO-alpha(1-73), GRO-alpha(6-73), Gro1, GRO1 oncogene (melanoma growth stimulating activity, alpha), GRO1 oncogene (melanoma growth-stimulating activity), Gro1 oncogene, GROa, GROA, Growth-regulated alpha protein, KC, KC chemokine, mouse, homolog of, melanoma growth stimulatory activity alpha, Melanoma growth stimulatory activity, Melanoma growth stimulatory activity, alpha, MGSA alpha, MGSA, MGSA-a, N51, NAP-3, NAP3, Neutrophil-activating protein 3, Platelet-derived growth factor-inducible protein KC, Scyb 1, Scyb1, Secretory protein N51, Small inducible cytokine subfamily B, member 1

Immunogen: Synthetic peptide of human CXCL1

Swissprot: P09341
Gene Accession: NP001502

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.02 mg/mL
Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.