CXCL5 polyclonal, anti-rat

Quantity: 100 µg

Background:
C-X-C motif chemokine 5 or ENA-78 is a protein that in humans is encoded by the CXCL5 gene. The protein encoded by this gene, CXCL5 is a small cytokine belonging to the CXC chemokine family. It is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. Expression of CXCL5 has also been observed ineosinophils, and can be inhibited with the type II interferon IFN-γ. This chemokine stimulates the chemotaxis of neutrophils possessing angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2. The gene for CXCL5 is encoded on four exons and is located on human chromosome 4 amongst several other CXC chemokine genes. CXCL5 has been implicated in connective tissue remodelling. Also, CXCL5 has been described to regulate neutrophil homeostasis.

Description:
Rabbit IgG polyclonal antibody for C-X-C motif chemokine 5 (CXCL5) detection. Tested with WB, ELISA in Rat.

Synonyms:
AMCFII antibody, C-X-C motif chemokine 5 antibody, chemokine (C-X-C motif) ligand 5 antibody, Cxcl5 antibody, CXCL5_HUMAN antibody, ENA-78 (8-78) antibody, ENA-78(1-78) antibody, ENA-78(9-78) antibody, ENA78 antibody, Epithelial derived neutrophil activating protein 78 antibody, Epithelial-derived neutrophil-activating protein 78 antibody, Lipopolysaccharide-induced CXC chemokine antibody, Neutrophil activating peptide ENA 78 antibody, Neutrophil-activating peptide ENA-78 antibody, neutrophil-activating protein 78 antibody, SCYB5 antibody, Small inducible cytokine B5 antibody, small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78) antibody, small inducible cytokine subfamily B, member 5 antibody, Small-inducible cytokine B5 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E. coli-derived rat CXCL5 recombinant protein (Position: A38-Q130). Rat CXCL5 shares 58.7% and 76.3% amino acid (aa) sequence identity with human and mouse CXCL5, respectively.E. coli-derived rat CXCL5 recombinant protein (Position: A38-Q130). Rat CXCL5 shares 58.7% and 76.3% amino acid (aa) sequence identity with human and mouse CXCL5, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: rat

Applications: WB, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.