CXCL5 Polyclonal Antibody

Background:
CXCL5 (C-X-C Motif Chemokine Ligand 5) is a Protein Coding gene. Diseases associated with CXCL5 include Pediatric Ulcerative Colitis and Acute Cervicitis. Among its related pathways are Peptide ligand-binding receptors and Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions. GO annotations related to this gene include chemokine activity and CXCR chemokine receptor binding. An important paralog of this gene is CXCL6.This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion.

Research Area: Cancer, Cardiovascular, Immunology

Synonyms:
AMCFII, C-X-C motif chemokine 5, C-X-C motif chemokine ligand 5, chemokine (C-X-C motif) ligand 5, Cxcl5, CXCL5, ENA 78, ENA-78 (8-78), ENA-78(1-78), ENA-78(9-78), ENA78, Epithelial derived neutrophil activating protein 78, Epithelial-derived neutrophil-activating protein 78, Lipopolysaccharide-induced CXC chemokine, Neutrophil activating peptide ENA 78, Neutrophil-activating peptide ENA-78, neutrophil-activating protein 78, SCYB5, Small inducible cytokine B5, small inducible cytokine subfamily B (Cys-X-Cys), member 5 (epithelial-derived neutrophil-activating peptide 78), small inducible cytokine subfamily B, member 5, Small-inducible cytokine B5

Immunogen: Synthetic peptide of human CXCL5

Swissprot: P42830
Gene Accession: NP002985

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: IHC 1:40-1:250, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.