CXCR3 polyclonal, anti-human, mouse

Background:
This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).

Synonyms: CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR

Cellular Location: Cell membrane Multi-pass membrane protein

Immunogen:
A synthetic peptide of human CXCR3

Gene Symbol: CXCR3

Gene ID: 2833

Swiss prot: P49682

Calculated MW: 41kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.