CXCR4 N-terminal region polyclonal, anti-human, mouse, rat, rabbit, pig, horse

CXCR4 N-terminal region polyclonal, anti-human, mouse, rat, rabbit, pig, horse

€474.00
In stock
SKU
AC-AI10012
Catalog Number: AC-AI10012
Size: 50 µg
Isotype: rabbit IgG
Applications: WB, IHC, FC
Datasheet
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Background:
This is a rabbit polyclonal antibody against CXCR4. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein.

Other Names:
C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, Leukocyte-derived seven transmembrane domain receptor, LESTR, Lipopolysaccharide-associated protein 3, LAP-3, LPS-associated protein 3, NPYRL, Stromal cell-derived factor 1 receptor, SDF-1 receptor, CD184, CXCR4

Target/Specificity:
CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Immunogen:
The immunogen for anti-CXCR4 antibody: synthetic peptide directed towards the N terminal of human CXCR4

Gene Name:
CXCR4
Gene Name:
7852
Swissprot ID: P61073
NCBI Accession:
NP_003458
Primary Accession: P61073
Other Accession: P61073;NP_003458;NM_003467
Purification: Affinity Purified
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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