CXCR4 Polyclonal Antibody

Background:
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research Area: Cancer, Metabolism, Immunology, Microbiology, Neuroscience, Stem Cells

Synonyms:
CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS, CXCR4

Immunogen: A synthetic peptide of human CXCR4 (NP_003458.1).

Swissprot: P61073
Gene ID: 7852

Calculated MW: 39 kDa/40 kDa
Observed MW: 36 kDa/70 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:1000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.