CXCR4 polyclonal(N-term), anti-human

CXCR4 polyclonal(N-term), anti-human

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In stock
SKU
AC-AP19500A
Catalog Number: AC-AP19500A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB41207
Applications: WB
Datasheet

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Background:
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

Other Names:
C-X-C chemokine receptor type 4, CXC-R4, CXCR-4, FB22, Fusin, HM89, LCR1, Leukocyte-derived seven transmembrane domain receptor, LESTR, Lipopolysaccharide-associated protein 3, LAP-3, LPS-associated protein 3, NPYRL, Stromal cell-derived factor 1 receptor, SDF-1 receptor, CD184, CXCR4

Target/Specificity:
This CXCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human CXCR4.

Antigen Region:
50-79

Antigen Type: Synthetic Peptide

Gene Name: CXCR4
Gene ID: 7852
Primary Accession: P61073
NCBI Accession: NP_001008540.1;NP_003458.1
Other Accession: O08565; Q764M9; P70658; Q28474; P25930; NP_001008540.1; Q28553
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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