CXCR5 polyclonal, anti-human, mouse, rat

Background:
Burkitt's lymphoma receptor 1 (Blr1) is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G-protein coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B-lymphocyte chemo-attractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B-cell migration into splenic and Peyer's patch follicles. BLC expression in Peyer's patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation.

Alternative Name:
CXC-R5, CXCR-5, MDR-15, CXCR5, BLR1, MDR15, BLR 1, BLR1, Burkitt lymphoma receptor 1, Burkitt lymphoma receptor 1 GTP binding protein, Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5), C X C chemokine receptor type 5, C-X-C chemokine receptor type 5, CD 185, CD185, CD185 antigen, Chemokine (C-X-C motif) receptor 5, Chemokine C X C motif receptor 5, Chemokine CXC motif receptor 5, Chemokine receptor 5, CXC chemokine receptor type 5, CXC R5, CXC-R5, CXCR 5, CXCR-5, Cxcr5, CXCR5, MDR 15, MDR-15, MDR15, MGC117347, Monocyte derived receptor 15, Monocyte-derived receptor 15,

Application Dilution:
WB:1:500-1:1,000
IHC:1:50-1:200
FC:1:50-1:100

Specificity: CXCR5 polyclonal antibody detects endogenous levels of CXCR5 protein.

Immunogen:
Recombinant protein

MW: 42 kDa

Swiss-Prot: P32302(Human) Q04683(Mouse) P34997(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.