CYBB C-terminal region polyclonal, anti-human, mouse, rat, rabbit, pig, horse, bovine, guinea pig, dog

Background:
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.

Other Names:
Cytochrome b-245 heavy chain, 1.-.-.-, CGD91-phox, Cytochrome b(558) subunit beta, Cytochrome b558 subunit beta, Heme-binding membrane glycoprotein gp91phox, NADPH oxidase 2, Neutrophil cytochrome b 91 kDa polypeptide, Superoxide-generating NADPH oxidase heavy chain subunit, gp91-1, gp91-phox, p22 phagocyte B-cytochrome, CYBB, NOX2

Immunogen:
The immunogen for Anti-CYBB antibody is: synthetic peptide directed towards the C-terminal region of Human CYBB

Gene Name:
CYBB (HGNC:2578)
Gene Name:
1536
NCBI Accession:
NP_000388
Primary Accession: P04839
Other Accession: NM_000397;NP_000388
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.