Cyclin A2 Polyclonal Antibody

Background:
CCNA2 belongs to the highly conserved cyclin family,whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1,which is present only in germ cells,this cyclin is expressed in all tissues tested. CCNA2 binds and activates CDC2 or CDK2 kinases,and thus promotes both cell cycle G1/S and G2/M transitions.

Research Area: Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling

Synonyms:
Cyclin A2, Cyclin-A, CCN1, CCNA, Cyclin-A2, Cyclin A.

Immunogen: Recombinant Human Cyclin-A2 protein

Swissprot: P20248

Purification Method: Affinity purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 2 mg/mL
Dilution: IHC 1:100-1:400

Storage:
Store at -20°C. Avoid freeze / thaw cycles.