Cyclin B1 Polyclonal Antibody

Background:
G2/mitotic-specific cyclin-B1 is a protein that in humans is encoded by the CCNB1 gene. The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
CCNB 1, CCNB, ccnb1, CCNB1, Cyclin B1, G2 mitotic specific cyclin B1, G2/mitotic-specific cyclin-B1

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Cyclin B1

Swissprot: P14635,P24860,P30277

Calculated MW: 55 kDa
Observed MW: 55 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Concentration: 270 μg/mL
Dilution: WB 1:500-1:2000, IHC 1:300-1:500, IF 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Citation(s):
https://www.mdpi.com/1420-3049/24/1/121