Cyclin D1 rabbit polyclonal, anti-human, mouse, rat

Backgroud: Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.

Synonyms: CCND1, BCL1, D11S287E, PRAD1, U21B31, Cyclin D1

Gene Name: CCND1

Gene ID: 595

SwissProt ID: P24385

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.