Cyclin D2 (clone CY-D2), anti-human, mouse

Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Signal Transduction, Cell Growth and Death, Cell Communication, Infectious Diseases

Description:
Cyclin D2 is the regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1. Cyclin D2 regulates the cell-cycle during G1/S transition. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.

Alternate Names: Cyclin D2, G1/S-specific cyclin-D2, CCND2

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; ICC: 1:100-1:500

Accession No.: P30279

Antigen: Recombinant human cyclin D2 protein.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by anti-mouse IgG affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.