Cyclin D2 polyclonal, anti-human

Quantity: 100 µg

Background:
Cyclin D2, also known as CCND2, is a human gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin D2 is mapped to 12p13. The expression of pseudogene cyclin D2 mRNA in the human ovary increases with age, which may be a novel marker for decreased ovarian function associated with the aging process. High level expression of this gene was observed in ovarian and testicular tumors.

Description:
Rabbit IgG polyclonal antibody for G1/S-specific cyclin-D2 (CCND2) detection. Tested with IHC-P in Human.

Synonyms:
CCND 2 antibody, CCND2 antibody, CCND2_HUMAN antibody, CyclinD2 antibody, G1/S specific cyclin D2 antibody, G1/S-specific cyclin-D2 antibody, KIAK0002 antibody, MGC102758 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Cyclin D2 recombinant protein (Position: H157-L289). Human Cyclin D2 shares 87% and 89% amino acid (aa) sequences identity with mouse and rat Cyclin D2, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.