Cyclin F polyclonal, anti-human, mouse, rat antibody
€220.00
In stock
SKU
AC-ABV11444-50
Catalog Number: AC-ABV11444-50
Size: 50 µl
Host: Rabbit IgG
Applications: WB, IHC
Datasheet
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Size: 50 µl
Host: Rabbit IgG
Applications: WB, IHC
Datasheet
Request Information
Background:
Cyclin F is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. It is ubiquitously expressed in human cells but fluctuates dramatically through the cell cycle, peaking in G2 like cyclin A and decreasing prior to decline of cyclin B. Cyclin F exhibits regulated subcellular localization, being localized in the nucleus in most cells, with a significant percentage of cells showing only perinuclear staining.
Other Names:
F-box only protein 1, CCNF, FBX1, FBXO1, G2/mitotic-specific cyclin-F
Primary Accession: P41002
Gene Name: CCNF
Gene ID: 899
Concentration (mg/ml): 1 mg/ml
Cyclin F is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. It is ubiquitously expressed in human cells but fluctuates dramatically through the cell cycle, peaking in G2 like cyclin A and decreasing prior to decline of cyclin B. Cyclin F exhibits regulated subcellular localization, being localized in the nucleus in most cells, with a significant percentage of cells showing only perinuclear staining.
Other Names:
F-box only protein 1, CCNF, FBX1, FBXO1, G2/mitotic-specific cyclin-F
Primary Accession: P41002
Gene Name: CCNF
Gene ID: 899
Concentration (mg/ml): 1 mg/ml
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