Cyclin F rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified. [provided by RefSeq, Jul 2008],developmental stage:G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.,function:Likely to be involved in the control of the cell cycle during S phase and G2.,similarity:Belongs to the cyclin family.,similarity:Belongs to the cyclin family. Cyclin AB subfamily.,similarity:Contains 1 F-box domain.,

Synonyms: CCNF, FBX1, FBXO1, Cyclin-F, F-box only protein 1

Gene Name: CCNF

Gene ID: 899

SwissProt ID: P41002

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.