Cyclin H (clone 1H9-D3-E11), anti-human antibody
€295.00
In stock
SKU
AC-ABV12051-100
Catalog Number: AC-ABV12051-100
Size: 100 µg
Host: Mouse IgG
Applications: WB, IP
Datasheet
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Size: 100 µg
Host: Mouse IgG
Applications: WB, IP
Datasheet
Request Information
Background:
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Other Names:
Cyclin-H, MO15-associated protein, p34, p37
Primary Accession: P51946
Gene Name: CCNH
Gene ID: 902
Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
Other Names:
Cyclin-H, MO15-associated protein, p34, p37
Primary Accession: P51946
Gene Name: CCNH
Gene ID: 902
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