Cyclin H polyclonal, anti-human
€388.00
In stock
SKU
BS6099
Background:
Cyclin H belongs to the highly conserved cyclin family, and are regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin H forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, and thus functions as a CDK-activating kinase (CAK). Cyclin H and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes.
Alternative Name:
Cyclin-H, MO15-associated protein, p34, p37, CCNH
Application Dilution: WB: 1:500 - 1:2000, IP: 1:50 - 1:200
Specificity: CCNH polyclonal antibody detects endogenous levels of CCNH protein.
Immunogen:
Recombinant full length Human Cyclin H.
MW: ~ 38 kDa
Swis Prot.: P51946
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Cyclin H belongs to the highly conserved cyclin family, and are regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin H forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, and thus functions as a CDK-activating kinase (CAK). Cyclin H and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes.
Alternative Name:
Cyclin-H, MO15-associated protein, p34, p37, CCNH
Application Dilution: WB: 1:500 - 1:2000, IP: 1:50 - 1:200
Specificity: CCNH polyclonal antibody detects endogenous levels of CCNH protein.
Immunogen:
Recombinant full length Human Cyclin H.
MW: ~ 38 kDa
Swis Prot.: P51946
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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