Cyclophilin A polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Cyclophilin A(PPIA),Peptidylprolyl isomerase A,is an enzyme that in humans is encoded by the PPIA gene.Using chromosome 7 and chromosome 10 deletion hybrid panels, the PPIA coding gene is localized to 7p13-p11.2. This gene encodes a member of the peptidyl-prolyl cis-trans isomerase(PPIase) family. Cyclophilin A is a member of the immunophilin class of proteins that all possess peptidyl-prolyl cis/trans isomerase activity and are believed to be involved in protein folding and/or intracellular protein transport. Cyclophilin A binds to the Gag protein of human immunodeficiency virus type 1(HIV-1). Cyclophilin A may have an essential function in HIV-1 replication.may have an essential function in HIV-1 replication.

Description:
Rabbit IgG polyclonal antibody for Peptidyl-prolyl cis-trans isomerase A (PPIA) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Cyclophilin A, Cyclosporin A-binding protein, Rotamase A

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human Cyclophilin A(54-71aa HRIIPGFMCQGCDFTRHN), different from the related mouse and rat sequences by one amino acid.A synthetic peptide corresponding to a sequence at the N-terminus of human Cyclophilin A(54-71aa HRIIPGFMCQGCDFTRHN), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.