Cyclophilin B polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Peptidyl-prolyl cis-trans isomerase B, also known as CYPB, is an enzyme that in humans is encoded by the PPIB gene. This gene is mapped to 15q22.31. The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.

Description:
Rabbit IgG polyclonal antibody for Peptidyl-prolyl cis-trans isomerase B (PPIB) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
AA408962 antibody, AA553318 antibody, AI844835 antibody, Cphn 2 antibody, Cphn2 antibody, Cyclophilin B antibody, Cyclophilin like protein antibody, CyP 20b antibody, CYP S1 antibody, CYP-S1 antibody, CYPB antibody, EC 5.2.1.8 antibody, MGC14109 antibody, MGC2224 antibody, OI9 antibody, peptidyl prolyl cis trans isomerase B antibody, Peptidyl prolyl cis trans isomerase B precursor antibody, Peptidyl-prolyl cis-trans isomerase B antibody, Peptidyl-prolyl cis-trans isomerase B precursor antibody, peptidylprolyl isomerase B(cyclophilin B) antibody, Peptidylprolyl isomerase B antibody, PPIase antibody, PPIase B antibody, PPIB antibody, PPIB_HUMAN antibody, Rotamase antibody, Rotamase B antibody, S cyclophilin antibody, S-cyclophilin antibody, SCYLP antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Cyclophilin B(176-196aa MEVVRKVESTKTDSRDKPLKD), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human.
Predicted to work with: mouse, rat.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.