CYFIP1 polyclonal, anti-human, mouse, rat

Background:
CYFIP1 are cytoplasmic proteins belonging to the CYFIP family. Both proteins bind GTP-bound Rac 1 to release FRM1 in its active state, which is thought to regulate mRNA translation of neural cytoskeletal proteins. A loss of CYFIP1 and CYFIP2 leads to mutant neurons with defective axonal growth and motor function. Also designated specifically Rac1-associated protein 1 (sra-1) or p140sra-1, CYFIP1 contains 1,253 amino acids and is a component of the WAVE2 complex.

Synonyms: P140SRA-1, SHYC, SRA-1, SRA1

Cellular Location: Cell junction Cell projection Cytoplasm lamellipodium perinuclear region ruffle synapse synaptosome

Immunogen:
Recombinant protein of human CYFIP1

Gene Symbol: CYFIP1

Gene ID: 23191

Swiss prot: Q7L576

Calculated MW: 145kDa

Recommended dilution:
WB 1:1000-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.