CYP11A1 Polyclonal Antibody

Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
Cholesterol 20 22 desmolase, Cholesterol desmolase, Cholesterol monooxygenase (side chain cleaving), Cholesterol side chain cleavage enzyme, Cholesterol side chain cleavage enzyme mitochondrial, Cholesterol side-chain cleavage enzyme, CP11A, CYP11A, CYP11A1, CYPXIA1, Cytochrome P450 11A1, Cytochrome P450 11A1 mitochondrial, Cytochrome P450 family 11 subfamily A polypeptide 1, Cytochrome P450 subfamily XIA, Cytochrome P450(scc), Cytochrome P450C11A1, mitochondrial, P450SCC, Steroid 20 22 lyase

Immunogen: Recombinant protein of human CYP11A1

Swissprot: P05108
Gene Accession: BC032329

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.6 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-18040/sc-18043/sc-292456