CYP11B1 Polyclonal Antibody

Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
CPN1, CYP11B, CYPXIB1, Cytochrome P 450c11, Cytochrome P450 11B1, mitochondrial, Cytochrome p450 XIB1, Cytochrome P450, family 11, subfamily B, polypeptide 1, Cytochrome P450, subfamily XIB (steroid 11 beta hydroxylase), polypeptide 1, Cytochrome P450, subfamily XIB, polypeptide 1, Cytochrome P450C11, FHI, P 450C11, P450C11, S11BH, Steroid 11 beta hydroxylase, Steroid 11 beta monooxygenase

Immunogen: Recombinant protein of human CYP11B1

Swissprot: P15538
Gene Accession: BC096285

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-47649/sc-47647/sc-32372