CYP11B1 Polyclonal Antibody

Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
CYP11B1, CPN1, CYP11B, FHI, P450C11

Immunogen: Recombinant fusion protein of human CYP11B1 (NP_000488.3).

Swissprot: P15538
Gene ID: 1584

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.