CYP11B2 polyclonal (Center), anti-human, mouse

CYP11B2 polyclonal (Center), anti-human, mouse

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In stock
SKU
AC-AP11213C
Catalog Number: AC-AP11213C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16930
Applications: WB, FC, IHC-P
Datasheet

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Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency.

Other Names:
Cytochrome P450 11B2, mitochondrial, Aldosterone synthase, ALDOS, Aldosterone-synthesizing enzyme, CYPXIB2, Cytochrome P-450Aldo, Cytochrome P-450C18, Steroid 18-hydroxylase, CYP11B2

Target/Specificity:
This CYP11B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-147 amino acids from the Central region of human CYP11B2.

Antigen Region:
120-147

Antigen Type: Synthetic Peptide

Gene Name: CYP11B2 {ECO:0000303|PubMed:1346492, ECO:0000312|HGNC:HGNC:2592}
Gene ID: 1585
Primary Accession: P19099
NCBI Accession: NP_000489.3
Other Accession: NP_000489
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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