CYP1A1 monoclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AM2174b
Catalog Number: AC-AM2174b
Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 655CT6.1.2
Applications: WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 655CT6.1.2
Applications: WB
Datasheet
Request Information
Background:
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
Other Names:
Cytochrome P450 1A1, CYPIA1, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1, CYP1A1
Target/Specificity:
This CYP1A1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 377-405 amino acids from the C-terminal region of human CYP1A1.
Antigen Region:
377-405
Antigen Type: Synthetic Peptide
Gene Name: CYP1A1 {ECO:0000303|PubMed:10681376, ECO:0000312|HGNC:HGNC:2595}
Gene ID: 1543
Primary Accession: P04798
NCBI Accession: NP_000490.1
Other Accession: P33616; NP_000490
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
Other Names:
Cytochrome P450 1A1, CYPIA1, Cytochrome P450 form 6, Cytochrome P450-C, Cytochrome P450-P1, CYP1A1
Target/Specificity:
This CYP1A1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 377-405 amino acids from the C-terminal region of human CYP1A1.
Antigen Region:
377-405
Antigen Type: Synthetic Peptide
Gene Name: CYP1A1 {ECO:0000303|PubMed:10681376, ECO:0000312|HGNC:HGNC:2595}
Gene ID: 1543
Primary Accession: P04798
NCBI Accession: NP_000490.1
Other Accession: P33616; NP_000490
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
|---|
Write Your Own Review