CYP1A1 Polyclonal Antibody

Background:
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
AHH, AHRR, Aryl hydrocarbon hydroxylase, CP11, CP1A1, CYP 1, CYP1, cyp1a1, CYPIA1, Cytochrome P1 450 dioxin inducible, Cytochrome P1-450, Cytochrome P450 1A1, Cytochrome P450 family 1 subfamily A polypeptide 1, Cytochrome P450 form 6, Cytochrome P450 subfamily I (aromatic compound inducible) polypeptide 1, Cytochrome P450-C, Cytochrome P450-P1, Flavoprotein-linked monooxygenase, Microsomal monooxygenase, P1 450, P450 C, P450 form 6, P450 P1, P450DX, Xenobiotic monooxygenase

Immunogen: Recombinant protein of human CYP1A1

Swissprot: P04798
Gene Accession: BC023019

Calculated MW: 58 kDa
Observed MW: Refer to figures

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-9828/sc-48432/sc-20772