CYP1B1 antibody (clone 2F8), anti-human

Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.

Other Names:
Cytochrome P450 1B1, CYPIB1, CYP1B1

Antigen Type:
Recombinant Protein

Gene Name: CYP1B1 {ECO:0000303|PubMed:8910454, ECO:0000312|HGNC:HGNC:2597}
Gene ID: 1545
NCBI Accession: NP_000095.2
Primary Accession: Q16678
Other Accession: NM_000104
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .