CYP1B1 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.

Synonyms: ASGD6, CP1B, CYPIB1, GLC3A, P4501B1

Cellular Location: Endoplasmic reticulum membrane Microsome membrane Mitochondrion Peripheral membrane protein

Immunogen:
Recombinant protein of human CYP1B1

Gene Symbol: CYP1B1

Gene ID: 1545

Swiss prot: Q16678

Calculated MW: 61kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.