CYP24A1 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP21361b
Catalog Number: AC-AP21361b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB51760
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB51760
Applications: WB
Datasheet
Request Information
Background:
Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23- hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
Other Names:
25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450 24A1, Cytochrome P450-CC24, CYP24A1, CYP24
Target/Specificity:
This CYP24A1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 480-514 amino acids from the C-terminal region of human CYP24A1.
Gene Name: CYP24A1 (HGNC:2602)
Gene ID: 1591
Primary Accession: Q07973
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23- hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
Other Names:
25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450 24A1, Cytochrome P450-CC24, CYP24A1, CYP24
Target/Specificity:
This CYP24A1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 480-514 amino acids from the C-terminal region of human CYP24A1.
Gene Name: CYP24A1 (HGNC:2602)
Gene ID: 1591
Primary Accession: Q07973
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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