CYP27B1 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP12284b
Background:
This gene encodes a member of the cytochrome P450superfamily of enzymes. The cytochrome P450 proteins aremonooxygenases which catalyze many reactions involved in drugmetabolism and synthesis of cholesterol, steroids and other lipids.The protein encoded by this gene localizes to the innermitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3at the 1alpha position. This reaction synthesizes1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, whichbinds to the vitamin D receptor and regulates calcium metabolism.Thus this enzyme regulates the level of biologically active vitaminD and plays an important role in calcium homeostasis. Mutations inthis gene can result in vitamin D-dependent rickets type I.
Other Names:
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial, 25-OHD-1 alpha-hydroxylase, 25-hydroxyvitamin D(3) 1-alpha-hydroxylase, VD3 1A hydroxylase, Calcidiol 1-monooxygenase, Cytochrome P450 subfamily XXVIIB polypeptide 1, Cytochrome P450C1 alpha, Cytochrome P450VD1-alpha, Cytochrome p450 27B1, CYP27B1, CYP1ALPHA, CYP27B
Gene Name: CYP27B1
Gene ID: 1594
Primary Accession: O15528
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a member of the cytochrome P450superfamily of enzymes. The cytochrome P450 proteins aremonooxygenases which catalyze many reactions involved in drugmetabolism and synthesis of cholesterol, steroids and other lipids.The protein encoded by this gene localizes to the innermitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3at the 1alpha position. This reaction synthesizes1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, whichbinds to the vitamin D receptor and regulates calcium metabolism.Thus this enzyme regulates the level of biologically active vitaminD and plays an important role in calcium homeostasis. Mutations inthis gene can result in vitamin D-dependent rickets type I.
Other Names:
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial, 25-OHD-1 alpha-hydroxylase, 25-hydroxyvitamin D(3) 1-alpha-hydroxylase, VD3 1A hydroxylase, Calcidiol 1-monooxygenase, Cytochrome P450 subfamily XXVIIB polypeptide 1, Cytochrome P450C1 alpha, Cytochrome P450VD1-alpha, Cytochrome p450 27B1, CYP27B1, CYP1ALPHA, CYP27B
Gene Name: CYP27B1
Gene ID: 1594
Primary Accession: O15528
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review