CYP2C18 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms: CPCI, CYP2C, CYP2C17, P450-6B/29C, P450IIC17

Cellular Location: Endoplasmic reticulum membrane Microsome membrane Peripheral membrane protein

Immunogen:
Recombinant protein of human CYP2C18

Gene Symbol: CYP2C18

Gene ID: 1562

Swiss prot: P33260

Calculated MW: 56kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.