CYP2R1 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP7894b
Catalog Number: AC-AP7894b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB17016
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB17016
Applications: IHC-P, WB
Datasheet
Request Information
Background:
CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.
Other Names:
Vitamin D 25-hydroxylase, Cytochrome P450 2R1, CYP2R1
Target/Specificity:
This CYP2R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-496 amino acids from the C-terminal region of human CYP2R1.
Antigen Region:
464-496
Antigen Type: Synthetic Peptide
Gene Name: CYP2R1
Gene ID: 120227
Primary Accession: Q6VVX0
NCBI Accession: NP_078790.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency.
Other Names:
Vitamin D 25-hydroxylase, Cytochrome P450 2R1, CYP2R1
Target/Specificity:
This CYP2R1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 464-496 amino acids from the C-terminal region of human CYP2R1.
Antigen Region:
464-496
Antigen Type: Synthetic Peptide
Gene Name: CYP2R1
Gene ID: 120227
Primary Accession: Q6VVX0
NCBI Accession: NP_078790.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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