CYP3A4 polyclonal, anti-human

Background:
CYP3A, the most abundant p450 enzyme in human liver, is responsible for the metabolism of more than 50% of the clinical test & lt, RTI ID = 0.0 & gt, (cYP3A) genes encode monooxygenases-enzymes which catalyze drug metabolism and the synthesis of cholesterol, steroids and other lipids. CYP3A family members localize in organs that associate with drug disposition, including the liver, gastrointestinal tract and kidney. The CYP3A cluster maps to gene locus 7q22.1 and consists of four genes (CYP3A4, CYP3A5, CYP3A7 and CYP3A43) and two pseudogenes ( CYP3A4 is abundant in the endoplasmic reticulum of liver cells and upper intestinal enterocytes. CYP3A4 expression is isducible by glucocorticoids pharmacological agents.

Alternative Name:
CYP3A4, CYP3A3, 1, 8-cineole 2-exo-monooxygenase, Albendazole monooxygenase, Albendazole sulfoxidase, CP33, CP34, CP3A4, CYP3, CYP3A, CYP3A3, CYP3A4, CYPIIIA3, CYPIIIA4, Cytochrome P450 3A3, Cytochrome P450 3A4, Cytochrome P450 family 3 subfamily A polypeptide 4, Cytochrome P450 HLp, Cytochrome P450 NF-25, Cytochrome P450 subfamily IIIA polypeptide 4, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4, Cytochrome P450-PCN1, Glucocorticoid inducible P450, HLP, MGC126680, NF 25, NF25, Nifedipine oxidase, P450 III steroid inducible, P450 PCN1, P450, family III, P450C3, P450PCN1, Quinine 3 monooxygenase, Quinine 3-monooxygenase, Taurochenodeoxycholate 6 alpha hydroxylase, Taurochenodeoxycholate 6-alpha-hydroxylase,

Application Dilution:
WB:1:500-1:1,000
IHC:1:50-1:200

Specificity: CYP3A4 polyclonal antibody detects endogenous levels of CYP3A4 protein.

Immunogen:
recombinant protein

MW: 57 kDa

Swiss-Prot: P08684(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.